Monoclonal Gammopathy of Undetermined Significance
نویسندگان
چکیده
Monoclonal gammopathies are a heterogeneous group of disorders characterized by the stable or progressive proliferation of an abnormal clone of plasma cells that continue pro‐ ducing antibodies [4]. But because these immunoglobulin proteins are abnormal and mon‐ oclonal (identical copies of each other), these offer no protection against infections and can damage the kidney. This monoclonal immunoglobulin is called M-protein. Each basic unit is a monomeric immunoglobulin consisting of two heavy chains of the same class and subclass and two light chains of the same type. The heavy chain classes are G, A, M, D, E (gamma, alpha, mu, delta, epsilon), while the light chain types are kappa (κ) and lambda (λ).
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Monoclonal Gammopathy of Undetermined Significance with Metastatic Carcinoma – A Rare Presentation
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